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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15
All Species:
22.73
Human Site:
T362
Identified Species:
50
UniProt:
P42566
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42566
NP_001153441.1
896
98656
T362
D
L
K
E
K
E
D
T
I
K
Q
R
T
S
E
Chimpanzee
Pan troglodytes
XP_001139393
896
98643
T362
D
L
K
E
K
E
D
T
I
K
Q
R
T
S
E
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
A518
D
I
R
E
K
E
E
A
I
R
Q
K
T
S
E
Dog
Lupus familis
XP_532580
889
97932
T349
D
L
K
E
K
E
D
T
I
K
Q
R
T
S
E
Cat
Felis silvestris
Mouse
Mus musculus
P42567
897
98453
T362
D
L
K
E
K
E
D
T
V
K
Q
R
T
S
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026454
920
100691
T398
D
L
K
E
K
E
D
T
I
K
Q
R
T
S
E
Frog
Xenopus laevis
O42287
1270
143652
K392
E
R
A
E
Q
E
R
K
E
R
E
R
Q
D
Q
Zebra Danio
Brachydanio rerio
XP_002663145
1039
114340
T395
D
I
K
D
R
E
E
T
I
R
Q
R
T
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122937
1043
116535
D398
D
I
A
Q
K
E
A
D
I
K
I
K
N
G
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
L160
D
I
Q
K
K
E
E
L
I
K
M
K
N
M
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34216
1381
150765
Q657
N
L
R
S
T
H
D
Q
N
V
K
Q
T
E
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
43.2
91.5
N.A.
89.3
N.A.
N.A.
N.A.
74.6
21
50.5
N.A.
N.A.
30.1
N.A.
29.6
Protein Similarity:
100
99.7
59.5
94.5
N.A.
93.4
N.A.
N.A.
N.A.
84.1
34.9
64.4
N.A.
N.A.
48.2
N.A.
44.3
P-Site Identity:
100
100
60
100
N.A.
93.3
N.A.
N.A.
N.A.
100
20
66.6
N.A.
N.A.
40
N.A.
40
P-Site Similarity:
100
100
93.3
100
N.A.
100
N.A.
N.A.
N.A.
100
53.3
100
N.A.
N.A.
60
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
0
10
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
82
0
0
10
0
0
55
10
0
0
0
0
0
10
0
% D
% Glu:
10
0
0
64
0
91
28
0
10
0
10
0
0
10
82
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
37
0
0
0
0
0
0
73
0
10
0
0
0
0
% I
% Lys:
0
0
55
10
73
0
0
10
0
64
10
28
0
0
0
% K
% Leu:
0
55
0
0
0
0
0
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% M
% Asn:
10
0
0
0
0
0
0
0
10
0
0
0
19
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
10
10
0
0
10
0
0
64
10
10
0
19
% Q
% Arg:
0
10
19
0
10
0
10
0
0
28
0
64
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
0
0
0
0
0
0
64
0
% S
% Thr:
0
0
0
0
10
0
0
55
0
0
0
0
73
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _